|Season 12, Episode 1|
|Air date||September 22, 2005|
|Written by||Lisa Zwerling, John Wells & Joe Sachs|
|Directed by||Christopher Chulack|
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Canon City is the 1st episode and the twelfth season premiere of "E.R."
SAM'S (LINDA CARDELLINI) SON ALEX RUNS AWAY TO FIND HIS FATHER: Sam (Linda Cardellini) and Kovac (Goran Visnjic) report Alex missing to the police and suspect that he is trying to find his father. Kovac and Sam are especially worried because Alex is diabetic and he has forgotten his insulin.
Neela (Parminder Nagra), Ray (Shane West) and Abby (Maura Tierney) struggle with their first shifts in charge of the new interns.
Mehki Phifer, Sherry Stringfield, and Scott Grimes also star.